Senior Director, Medical Operations & Project Management

Senior Director, Medical Operations And Project Management

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

As we continue to grow and expand globally, we seek a dynamic and experienced Senior Director, Medical Operations and Project Management to lead operational strategy and excellence across Medical Affairs. Reporting to the Head of Medical Excellence, this role will serve as a senior leader responsible for shaping, driving, and overseeing Medical Affairs operations, governance, project management infrastructure, and cross-functional execution. The Senior Director will be instrumental in enabling medical impact through operational leadership, strategic planning, systems enablement, and inspection readiness across the full product lifecycle. This highly visible role will collaborate across internal teams and external partners to deliver compliant, efficient, and scalable solutions that support global medical strategy, launch readiness, and scientific engagement.

Key responsibilities include:

• Strategic Operations Leadership
• Medical Affairs Program & Project Management
• Financial & Vendor Management
• Systems, Tools, and Digital Enablement
• Organizational Enablement & Leadership

Required Skills, Experience and Education:

• Advanced degree required (PharmD, PhD, MBA, or equivalent in life sciences or business); PMP certification strongly preferred.
• Minimum 15+ years (with MBA/Master's) or 13+ years (with PharmD/PhD) of progressive experience in biotech/pharma, with 8+ years in Medical Affairs operations, project management, or governance roles.
• Proven leadership in managing global Medical Affairs initiatives including launch operations, governance, compliance, congresses, and external engagement.
• Expertise in operational oversight of vendor contracts, budgets, audits, and inspections.
• Deep understanding of industry regulations (FDA, EMA, GxP, ICH, Sunshine Act, PhRMA, ACCME) and medical compliance standards.
• Demonstrated success implementing digital solutions and project governance frameworks within a matrixed environment.
• Strong financial acumen, strategic thinking, and ability to manage ambiguity in a fast-paced environment.
• Excellent interpersonal, communication, and influence skills with executive presence.

Preferred Skills:

• Oncology and/or precision medicine experience strongly preferred.
• Previous leadership of Medical Operations frameworks.
• Experience scaling Medical Affairs operations during rapid growth or product launch phases.
• Familiarity with global medical regulations and market access considerations (HTA, HEOR, IEP).

The base salary range for this full-time position is $236,000 to $295,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.