Engineer III

Takeda Development Center Americas, Inc. is seeking an Engineer III with the following duties:

Independently carry out bioreactor operations across various scales, ranging from 250ml to 10 L bioreactors;
Prepare experimental protocols, and support tech transfer of developed cell culture process to pilot team and manufacturing facility;
Design experiments, interpret the data independently, identify complex technical issues and implement solutions under supervision;
Contribute to technical reports through writing and consolidating technical documents;
Actively participate and interact with support process development, optimization, characterization, troubleshooting problems, supporting large scale studies, and supporting project goals;
Support technology transfer through writing and consolidating technical documents, reviewing batch records, coordinate within department as well as cross functionally with peers on projects;
Contribute to evaluation of new technology/equipment that can be applied across multiple programs;
Document data accurately as per established company guidelines and procedures;
Draft technical reports, memos, procedures, protocols, and presentations, provide organizational support and cross-functional project team participation and present to department and at project team meetings;
Execute bioreactor operations, clarifications, and purification using high throughput systems such as ambr250 and Tecan;
Up to 20% remote work allowed.

Requirements:

Master's degree in Chemistry, Biology, Pharmacy, Engineering, or related Pharmaceutical Science.
Prior experience must include: Execute bioreactor operations, primary clarification, and purification using high-throughput systems (e.g., ambr250, Tecan), and design experiments to assess and optimize process performance; Independently interpret experimental data, identify complex technical issues, and implement solutions under supervision. Contribute to the evaluation and integration of new technologies and equipment across multiple programs; Collaborate with cross-functional teams to support the tech transfer of processes to Pilot, Manufacturing, and external CDMOs, ensuring seamless integration of new processes and technologies; Author and revise technical documents, including SOPs and process development reports. Provide cross-training for team members on various analytical instruments and techniques. Conduct product quality testing using tools such as Solo-VPE, Lunatic, HPLC, UPLC, and UV spectrophotometer.

Full time. $104,000-$168,000 per year.

Locations: Lexington, MA

Worker Type: Employee

Worker Sub-Type: Regular

Time Type: Full time