Post - doctoral Research Fellow - Chromatin Regulator And Immune Interaction In Blood Cancers, Lab Of Jianping Li

Postdoctoral Fellow Opportunity

The laboratory of Dr. Jianping Li at Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Thomas Jefferson University (TJU) is seeking a highly motivated postdoctoral fellow to join our team. Dr. Li's lab focuses on the role of chromatin regulators and immune interaction in blood cancers, especially in the initiation of acute lymphoblastic leukemia and lymphoma, relapse, and chemotherapy resistance. We explore mutant chromatin regulators-driven phenotype and molecular mechanisms using cell lines, conditional mouse models, patient-derived xenografts (PDXs), and cutting-edge technologies such as CUT&RUN, ChIP-Seq, single-cell RNA-Seq, ATAC-Seq, Hi-C, proteomics, drug screening, flow cytometry and sorting, and CRISPR editing and screening.

Eligibility Requirements: We are looking for highly motivated and enthusiastic postdoctoral fellows with a recent PhD or MD or PhD/MD in biochemistry and molecular biology, bioinformatics, computational biology, hematology, immunology, cancer biology, or related fields. The candidate should have a strong interest in one of the following basic and translational research areas related to chromatin regulation, cancer epigenetics, stem cell biology, immune interaction, and developing targeted therapy.

Work Shift: Workday Day (United States of America)

Worker Sub Type: Regular

Primary Location Address: 951 Locust Street, Philadelphia, Pennsylvania, United States of America

Institute: Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Jefferson is recognized as high performing in cancer care by U.S. News & World Report and is designated a Comprehensive Cancer Center by the National Cancer Institute (NCI) for excellence in cancer care, prevention measures, and research. The NCI-designated SKCCC at TJU is home to national thought leaders across multiple cancer research disciplines and multi-institutional collaborations, announcing the expansion and deepening of hematologic malignancy research with the Blood Cancer Center of Excellence (BCCE). Our faculty lead paradigm-shifting research into the initiation and progression of cancers, as well as resistance mechanisms and potential target therapies. Here, researchers work collaboratively across multiple departments and specialties to address some of the greatest complications in healthcare.

Jefferson, which is principally located in the greater Philadelphia region, Lehigh Valley and Northeastern Pennsylvania and southern New Jersey, is reimagining health care and higher education to create unparalleled value. Jefferson is more than 65,000 people strong, dedicated to providing the highest-quality, compassionate clinical care for patients; making our communities healthier and stronger; preparing tomorrow's professional leaders for 21st-century careers; and creating new knowledge through basic/programmatic, clinical and applied research.

Jefferson Health, nationally ranked as one of the top 15 not-for-profit health care systems in the country and the largest provider in the Philadelphia and Lehigh Valley areas, serves patients through millions of encounters each year at 32 hospitals campuses and more than 700 outpatient and urgent care locations throughout the region.

Jefferson Health Plans is a not-for-profit managed health care organization providing a broad range of health coverage options in Pennsylvania and New Jersey for more than 35 years.

Jefferson is committed to providing equal educational and employment opportunities for all persons without regard to age, race, color, religion, creed, sexual orientation, gender, gender identity, marital status, pregnancy, national origin, ancestry, citizenship, military status, veteran status, handicap or disability or any other protected group or status.

At Jefferson, we offer a comprehensive total rewards package designed to support the health and well-being of our colleagues and their families. It includes a wide range of benefits including competitive pay, health and retirement benefits, life and disability insurance, paid time off, educational benefits, financial and mental health resources and much more. Our diverse benefits offerings ensure you have the coverage and access to services you need to thrive both personally and professionally.