Research Service Professional (ipsc Editing Specialist)
Colorado Anschutz
Research Service Professional (iPSC Editing Specialist)
University of Colorado Anschutz Medical Campus
Department: Pharmacology / Functional Genomics Facility
Job Title: Research Service Professional (iPSC Editing Specialist)
Position #00839642 – Requisition # 37909
Job Summary:
We are urgently seeking a dynamic Research Scientist to lead a high-priority project focused on precision editing of induced pluripotent stem cells (iPSCs). This role is central to advancing our capabilities in disease modeling and therapeutic discovery in the field of Down Syndrome. The ideal candidate will have deep expertise in genome editing (e.g., CRISPR), stem cell biology, and functional genomics, and will drive innovation in editing strategies and platform development.
This is a pivotal opportunity to shape a transformative research initiative with broad translational impact. Join us in pushing the boundaries of stem cell engineering.
Key Responsibilities / Duties:
iPSC culture
CRISPR-mediated gene editing in iPSC lines
Perform RNA, DNA, and protein extraction and quality control, as well as other various molecular biology-related assays (qPCR, dPCR, western blot, amplicon sequencing, NGS library preparation, etc.)
Inventory, storage and management of biospecimens; associated record keeping
Manage edited iPSC inventory in collaboration with the Human Trisome Project biobank, Crnic Institute clinical trials, and associated investigations
Edited iPSC record keeping
Collaborate with researchers from other programs within the Crnic Institute (clinical, experimental models, data teams) to accomplish project goals and share research results
Assist senior staff in the design, execution and evaluation of research investigations, including literature reviews, performing experiments and pilots, data integration, and analysis
Foundational lab maintenance responsibilities
Assist with various laboratory and clinical support operations, such as autoclaving, inventories, ordering supplies, and hazardous materials management.
Prepare lab for daily operations, including stocking materials, equipment, safety, cleanliness, and related areas
Work Location: Onsite – this role is expected to work onsite and is located in Aurora, CO.
Why Join Us:
Join a mission-driven team at the forefront of precision medicine and genetic research. The Functional Genomics Shared Resource (FGSR), a leading core facility specializing in gene function analysis, has partnered with the Linda Crnic Institute for Down Syndrome—the largest academic hub for Down syndrome research globally. Together, we are advancing transformative science that directly improves health outcomes for individuals with Down syndrome.
As part of our iPSC team, you'll contribute to cutting-edge work in gene editing and functional validation of iPSC lines, helping build a gene-corrected iPSC panel that will serve as a foundational resource for future discoveries. You'll gain hands-on experience with CRISPR-based heterozygous gene editing technology, and a wide array of functional assays—all while working in a collaborative, intellectually stimulating environment.
We're looking for detail-oriented, motivated, and enthusiastic Laboratory Science Professionals who are passionate about making a real-world impact through science. If you thrive in fast-paced research setting and want to be part of a team that values innovation, precision, and purpose—this is your opportunity to make a difference.
Why work for the University?
We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:
Medical: Multiple plan options
Dental: Multiple plan options
Additional Insurance: Disability, Life, Vision
Retirement 401(a) Plan: Employer contributes 10% of your gross pay
Paid Time Off: Accruals over the year
Vacation Days: 22/year (maximum accrual 352 hours)
Sick Days: 15/year (unlimited maximum accrual)
Holiday Days: 10/year
Tuition Benefit: Employees have access to this benefit on all CU campuses
ECO Pass: Reduced rate RTD Bus and light rail service
There are many additional perks & programs with the CU Advantage.
Qualifications:
Minimum Qualifications:
A bachelor's degree in biology, molecular biology, chemistry, genetics, or a directly related field from an accredited institution
One (1) year of professional-level experience
Preferred Qualifications:
A master's degree in biology, molecular biology, chemistry, genetics, or a directly related field from an accredited institution
Two (2) years of professional-level experience
Individuals with advanced degree and research experience are encouraged to apply
Experience with iPSC maintenance, differentiation, and experimentation
Experience in CRISPR technology
Experience independently researching, synthesizing, and presenting novel and assigned topics.
Experience in training all ability levels (e.g., interns, colleagues) in sample processing procedures.
Competencies: Knowledge, Skills, and Abilities
Ability to communicate effectively, both in writing and orally.
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.
Ability to work with iPSC using established protocols.
Flexibility and adaptability to schedule changes, including occasional night and weekend hours.
Knowledge of aseptic technique and standard cell culture practices
Must be hard-working, independent yet team-oriented, flexible, and able to communicate effectively.
Self-motivated and highly organized, with demonstrated project planning and management skills in an academic research setting.
Strong qualitative analysis skills
Strong word processing skills, particularly with advanced Excel functions
Ability to manage the lab
Demonstrated ability to plan, present, and conduct independent experiments.
Willingness and working knowledge to assist the clinical research team and animal research team as needed.
Familiarity with genomic, gene expression, proteomic, and metabolomic platforms.
How to Apply:
For full consideration, please submit the following document(s):
A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position
Curriculum vitae / Resume
Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address
Questions should be directed to: Molishree Joshi, Molishree.joshi@cuanschutz.edu
Screening of Applications Begins: Immediately and continues until position is filled.
Anticipated Pay Range: $50,357 - $64,054
The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the